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Shigatoxin-positive farms have a high risk of outbreaks of edema disease following the ban on ZnO mid of 2022.

Edema (Oedema) disease (ED) is a mostly acute, often fatal, enterotoxemia. The mainly affected production stages are recently weaned pigs, pigs during nursery and younger finishing pigs. It´s caused by Shigatoxin (Stx2e), which is produced by specific virotypes of Escherichia coli (E. coli). The disease is characterized by edema at specific sites, sudden unexpected death, and also by neurologic signs related to lesions in the brain and sometimes mixed up inadvertently with clinical signs for Strep. suis infections.

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Edema (Oedema) disease (ED) is a mostly acute, often fatal, enterotoxemia. The mainly affected production stages are recently weaned pigs, pigs during nursery and younger finishing pigs. It´s caused by Shigatoxin (Stx2e), which is produced by specific virotypes of Escherichia coli (E. coli). The disease is characterized by edema at specific sites, sudden unexpected death, and also by neurologic signs related to lesions in the brain and sometimes mixed up inadvertently with clinical signs for Strep. suis infections.

While the Shigatoxin (Stx2e) encoding E. coli occur worldwide, prevalence data particularly from healthy herds are rarely available. A recently published prevalence study observed a high prevalence (37,4%) of Shigatoxin-encoding Escherichia coli (STEC) in pig farms. STEC positive farms are under particular risk for outbreaks of edema disease, especially when other control strategies such as supplementation of zinc oxide at therapeutic concentrations are no longer available (S. Mesonero-Escuredo et al., Vaccines, 2021).

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